Kisspeptin 10 benefits, Dosage, Side effects, Weight loss | Kisspeptin 10 vs Hcg

Kisspeptin-10 is a peptide that, in humans and other mammals, induces the release of gonadotropin. It is a cleavage product of the KISS1 metastasis suppressor gene and like other kisspeptin peptides, it has the same C-terminal decapeptide sequence. While kisspeptin-10's intrinsic bioactivity is comparable to that of longer kisspeptin fragments, it acts more quickly in rodents after intravenous injection and has a shorter half-life.

Kisspeptin 10 benefits

Research has demonstrated that kisspeptin may offer a number of advantages, such as:

Enhanced testosterone levels: Research has indicated that kisspeptin elevates testosterone levels, a crucial factor in reproductive well-being.

Enhanced fertility: Kisspeptin-10 has been proposed as a possible therapeutic target for the treatment of female infertile patients since it enhances the release of gonadotropin in men.

Potential therapeutic application: Kisspeptin has garnered attention as a prospective treatment option for various reproductive disorders, including infertility.

Anti-aging effects: Kisspeptin has been shown to reduce the formation of stress, which helps to improve UV-induced skin aging.

Anti-cancer properties: Kisspeptin has been shown to have anti-cancer properties.

Appetite control: Kisspeptin may have a part in controlling appetite control as it has been shown to lower serotonin and dopamine levels in the hypothalamus.

Kisspeptin 10 Dosage

Individualized Kisspeptin 10 dosages depend on factors like age, weight, and hormonal status. Studies suggest a range of 0.5µg to 2µg per kg body weight for stimulating gonadotropin release, starting with lower doses and adjusting as needed. 

Kisspeptin 10 Side effects

Dose-dependent: Headache, flushing, nausea, vomiting, and injection site reactions.

Allergic reactions: Rare, especially in those with allergies.

Seizures: Rare, especially in those with seizure disorders.

Kisspeptin-10 vs. HCG

Mechanism: Kisspeptin-10 stimulates hormone production indirectly, HCG mimics hormones directly.

Applications: Kisspeptin-10 for fertility/testosterone issues (investigational), HCG for fertility treatments and testosterone replacement.

Side effects: Kisspeptin-10: mostly mild (headache, flushing), HCG: wider range, including serious risks.

Key points: Kisspeptin-10 promising but not yet approved, HCG approved but requires caution.